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  • It was discovered that naltrexone and bupropion combined, which might be marketed down the road as Contrave, have better weight loss results than eating and working out alone.

    Using two separate drugs to lose weight naturally can be very effective there are combinations before the FDA now awaiting approval. When dealing with fat loss and the people who go through it you need to err along the side of caution and allow the FDA do its job and demand some investigation be done in order that the public is aware of the side effects and dangers of the medications before we bring them. Keep in mind that drug companies come in business to generate income and that they would say anything to keep people on their medications.

    Researchers found out that participants taking this drug for a year, lost weight within four weeks and have kept the body weight off through the entire 56 weeks in the study. Contrave is a combination of the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which can be made up of many active ingredient, which may make them more efficient and safer.

    Combo-pilling may be the newest fad or in addition to this the newest to come under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is now popular will be the fact that by right now there are no long term prescription diet pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be authorized by the FDA.

    Seizures really are a side effect with Contrave and must not be taken in people with seizure disorders. The drug may also raise blood pressure and heartrate, and shouldn't be used in people with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure levels and heartrate and must not be used in patients with uncontrolled high hypertension, along with by a person with heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients to the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.

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